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Research News - Success in Reversing Dementia in Mice Sets the Stage for Human Clinical Trials


Research News
Research News
2021-06-29
Researchers have identified a new treatment candidate that appears to not only halt neurodegenerative symptoms in mouse models of dementia and Alzheimer s disease, but also reverse the effects of the disorders.
The team, based at Tohoku University, published their results on June 8 in the International Journal of Molecular Sciences. The treatment candidate has been declared safe by Japan s governing board, and the researchers plan to begin clinical trials in humans in the next year.
There are currently no disease-modifying therapeutics for neurodegenerative disorders such as Alzheimer s disease, Lewy body dementia, Huntington disease and frontotemporal dementia in the world, said paper author Kohji Fukunaga, professor emeritus in Tohoku University s Graduate School of Pharmaceutical Sciences. We discovered the novel, disease-modifying therapeutic candidate SAK3, which, in our studies, rescued neurons in most protein-mis ....

Japan General , Kohji Fukunaga , Jing Xu , Ichiro Kawahata , Hisanao Izumi , Tohoku University Graduate School Of Pharmaceutical Sciences , International Journal Of Molecular Sciences , Drug Administration , Tohoku University , International Journal , Graduate School , ஜிங் ஐயூ , சர்வதேச இதழ் ஆஃப் மூலக்கூறு அறிவியல் , தோஹோக்கு பல்கலைக்கழகம் , சர்வதேச இதழ் , பட்டதாரி பள்ளி ,

Heavy rain hits wide areas of Japan

Heavy rain hits wide areas of Japan
japantoday.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from japantoday.com Daily Mail and Mail on Sunday newspapers.

Japan General , Japan Meteorological Agency ,

Promising preclinical results of new dementia treatment candidate sets the stage for human trials


Promising preclinical results of new dementia treatment candidate set the stage for human trials
Researchers have identified a new treatment candidate that appears to not only halt neurodegenerative symptoms in mouse models of dementia and Alzheimer s disease, but also reverse the effects of the disorders.
The team, based at Tohoku University, published their results on June 8 in the
International Journal of Molecular Sciences. The treatment candidate has been declared safe by Japan s governing board, and the researchers plan to begin clinical trials in humans in the next year.
There are currently no disease-modifying therapeutics for neurodegenerative disorders such as Alzheimer s disease, Lewy body dementia, Huntington disease and frontotemporal dementia in the world. We discovered the novel, disease-modifying therapeutic candidate SAK3, which, in our studies, rescued neurons in most protein-misfolding, neurodegenerative diseases. ....

Japan General , Kohji Fukunaga , Emily Henderson , Tohoku University Graduate School Of Pharmaceutical Sciences , International Journal Of Molecular Sciences , Drug Administration , Tohoku University , International Journal , Graduate School , எமிலி ஹென்டர்சன் , சர்வதேச இதழ் ஆஃப் மூலக்கூறு அறிவியல் , தோஹோக்கு பல்கலைக்கழகம் , சர்வதேச இதழ் , பட்டதாரி பள்ளி ,